What is Single-Pulse TMS (sTMS)?

sTMS

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sTMS stands for single-pulse transcranial magnetic stimulation, a breakthrough technology that delivers a gentle magnetic pulse to specific areas of your brain. These pulses are designed to interrupt abnormal brain activity associated with migraine attacks—before the pain escalates.

Unlike medications that work after symptoms begin or take time to build up in your system, sTMS works proactively by directly targeting the underlying neurological patterns responsible for migraine.

It’s safe. It’s FDA-cleared. And it’s something you can use at home.

sTMS Migraine Therapy

How Does It Work?

The sTMS device delivers a single magnetic pulse through the scalp to the cortex. This pulse is similar in strength to an MRI but focused and brief. It aims to modulate cortical excitability—a core factor in migraine initiation—without causing pain or requiring surgery.

Think of it as resetting an overloaded circuit in your brain.

With consistent use, sTMS can reduce the number of migraine days per month, lessen the severity of attacks, and for many patients, reduce the need for prescription drugs.

How is sTMS Different from rTMS?

You may have heard of repetitive TMS (rTMS) used in clinics for depression. sTMS is different in a few key ways:

Feature

Pulse Type

Delivery Site

Treatment Time

Approved Uses

Comfort Level

sTMS (eNeura)

Single, brief pulse

Home

Minutes

Migraine (with or without aura)

Gentle, painless

rTMS (Traditional)

Rapid, repetitive pulses

Clinical setting

20–40 minutes

Depression, OCD, smoking cessation

Can cause scalp discomfort

Features
sTMS (eNeura)

Pulse Type: Single, brief pulse

Delivery Site: Home

Treatment Time: Minutes

Approved Uses: Migraine (with or without aura)

Comfort Level: Gentle, painless

Features
rTMS (Traditional)

Pulse Type: Rapid, repetitive pulses

Delivery Site: Clinical setting

Treatment Time: 20–40 minutes

Approved Uses: Depression, OCD, smoking cessation

Comfort Level: Can cause scalp discomfort

Who is it For?

sTMS is FDA-cleared for the acute and preventive treatment of migraine in adults and adolescents aged 12 and older. It’s especially beneficial for people who:

  • Experience medication side effects
  • Are pregnant or breastfeeding
  • Have refractory or drug-resistant migraine
  • Want to avoid overuse of painkillers
  • Are exploring options beyond pharmaceuticals

It’s also being studied for Major Depressive Disorder (MDD), PTSD, and dual diagnosis conditions—with promising early results.

Safe, Personalized, and Easy to Use

Each patient receives a prescription and a tailored protocol. The device syncs with a mobile app to guide usage, track progress, and, in some cases, report outcomes to your doctor. It’s non-invasive, drug-free, and easily incorporated into daily life.

And because it’s safe to use at home, you stay in control—no appointments or office visits required.

Ready to Learn More?

At eNeura, we believe migraine should never hold you back from the life you deserve. Our mission is to make sTMS accessible, effective, and empowering for every patient who needs it.

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